Speakers

Prof. Alex Pui-Wai LEE
Professor, Department of Medicine & Therapeutics, Chinese University of Hong Kong, Hong Kong

Prof. Lee is a Professor in cardiology specialising in echocardiography and cardiac imaging. His main interests are heart valve disease, heart failure, structural heart intervention, stroke prevention in atrial fibrillation. He is the Director of the Echocardiography Laboratory and the Laboratory of Cardiac Imaging and 3D Printing, Prince of Wales Hospital, Faculty of Medicine, the Chinese University of Hong Kong.

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Abstract

Renal Outcome of NOAC: An Asian Perspective

Non-Vitamin K antagonist oral anticoagulants (NOACs) are now considered to be the standard of care for stroke prevention in AF patients by international guidelines. While all NOACs are approved in AF patients with a GFR of 30ml/min or above, there are differences in the proportion of drug excretion through kidney.  However, little evidence of clinical impact has been reviewed in this aspect.  Recently post hoc analysis from NOAC trials demonstrated less renal function decline with certain NOACs comparing with warfarin. Furthermore, another practice-based data from the United States also demonstrated similar renal protective effect of NOACs.  In this presentation, Prof. Alex Lee will discuss his recent analysis on renal function outcome in NOAC treated AF patients in Prince of Wales Hospital and provide insights from local setting.

 

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